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Updated ACB Assay Verification/Validation Programs

10/08/2018 10:57:40

Updated versions of the ACB assay verification/validation programs, authored by Prof Anders Kallner, have recently been uploaded to the ACB website (

Previously referred to as spreadsheets A-D, these have now been renamed to the following:

  1. Precision (imprecision) and trueness (bias) – previously “Spreadsheet A”
  2. Trueness (bias)
    1. From EQA materials - previously “Spreadsheet D”
    2. From reference materials - previously “Spreadsheet C”
  3. ROC analyses (NEW)
  4. Method comparison – previously “Spreadsheet B”

Instruction documents

Each program is now associated with an instruction document (in pdf format) which provides a brief background to the statistics used in each case. Each document and its associated program are listed under “Program & instructions”.

Example data

Dummy/example data are provided for each spreadsheet under the “Example data” heading. Instructions for analysing these data are given in the associated instruction document.


These programs have been independently verified. Copies of the data used for their testing and the associated verification documents are listed under the “Verification document & data” heading in each case. The code contained within these documents can be copied and pasted into any instance of the R statistical computing environment ( and, given the provided test data in each case, reproduce the verification analysis.

Kind regards,

Dr Ed Wilkes, Dr Zahra Khatami, and Prof Anders Kallner on behalf of the ACB Informatics Special Interest Group

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