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Trainees' Links - Molecular Biology

http://www.pcrlinks.com
Links to information about polymerase chain reaction techniques

OMIM -- Online Mendelian Inheritance in Man
OMIM is a database containing over 10,000 entries of human genes and genetic disorders with links to the NCBI Entrez database of MEDLINE articles. The home page has two sub-headings to ease the indexing of databases: Browse OMIM
Under this sub-heading it is possible to search the OMIM database (with provision to limit a search to a particular field), view the details about a gene regarding its location in the genome (OMIM Gene Map) and the result of its deficiency (OMIM Morbid Map). There is a key which allows interpretation of the aforementioned maps and an index to OMIM entries (OMIM numbering and symbols) which describes the 6-digit number each entry is allocated. The OMIM Gene Table provides an alphabetical list of the genes in the OMIM database. There is a useful update page which lists new additions and updates to the OMIM database.

ExPASy Molecular Biology Server
ExPASy describes each type of characterized enzyme for which an EC (Enzyme Commission) number has been allocated. The database is based upon the recommendations of the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (IUBMB).
It is easy to access and is well presented. A search will yield information such as the reaction catalysed and alternative names for the enzyme. Information on diseases resulting from a deficiency of the enzyme is also given.
The site has interactive access to a map of "Biochemical Pathways" (Boehringer Mannheim). This facility is not only useful for trainee biochemists but also for those interested in inherited metabolic disorders.
The site enables access to SWISSPROT, an annotated protein sequence database.
A visit to this site is highly recommended!
Reviewed by JB, IM

HUMAN GENE MAP at the National Center for Biotechnology Information

GenomeNet, Kyoto University, Japan
The encyclopedia of genes an genomes at the Institute for Chemical Research, Kyoto University, Japan - very large databases.

Examples of other databases include
Human Genes and Disease Maps
Cancer Genome Anatomy Project
Taxonomy Database

Send mail to trainees-webmaster@ACB.org.uk with questions or comments about this site.